Table of Contents
Animal Models in Obesity Research
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What Questions Have to be Answered ?
Mouse Models of Obesity and Type 2 Diabetes
Characteristics of the Metabolic Syndrome in the New Zealand Obese (NZO) Mouse Strain
Leptin Resistance in New Zealand Obese Mice
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Effects of High-fat Diet on Body Weight, Serum Insulin, and Prevalence of Diabetes in NZO Mice
Disease Development by Aberrant or Variant Genes
Identification of Susceptibility Loci
QTL for Obesity, Dyslipidemia, and Diabetes in the NZO-Backcross
Localization of the Obesity Susceptibility Locus Nob1
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Interaction of Genes and Nutrition: High-fat Diet Enhances the Effect of Nidd/SJL on Development of Type 2 Diabetes
Why is this Lifestyle so Resistant to Intervention?
Experimental Strategies to Identify Novel Targets
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Strategien zur Identifikation von Krankheitsgenen
Regulation of Food Intake, Thermogenesis, and Insulin Sensitivity by Leptin
Typischer Gewichtsverlauf während und nach Intervention durch Reduktionsdiät
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