Aberdeen, January 12-14, 2003 Perspectives: Molecular genetic research in human obesity Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps-University Marburg Johannes Hebebrand

27/05/2003


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Aberdeen, January 12-14, 2003 Perspectives: Molecular genetic research in human obesity Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps-University Marburg Johannes Hebebrand

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Confirmation of a major locus for human obesity

Phenotypes

Examples for behavioural and sensory phenotypes

Childhood and adolescent depression predicts obesity

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Combine research efforts in different species

Drosophila Mutant Collection

Process of Target Selection

Target Classes

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F2 Mangalitza x Piétrain porcine animals: Dichotomous circadian visiting pattern of feeding station

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Validation of an „obesity gene“

Validation of an „obesity gene“

High throughput genotyping

Situation

Problems

Solution

Example

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Procedure in multiple steps

Diagnostic and ethical issues

Author: Kinder und Jugendpsychiatrie